Wednesday, March 16, 2011

Location, location, location

DNA makes RNA makes protein makes life.
Changes in DNA nucleotide sequences (mutations) result in changes in proteins that have significant effects on the life processes they control.
A major way in which proteins interact with other proteins, especially receptors, is based on their shape and where they "live". If their amino acid sequence--determined by DNA codons--changes, they cannot go where they need to go and do what they need to do. The life processes of the affected cells change--often for the worse.
Such it is with malignant neoplasms. The changes in positioning of codons and subsequently in amino acid sequence and protein shape result in problems with location--where they can go and what they can do. In the end abnormal proteins and cells wander off to wreck havoc as parasites on the entire body, ultimately killing the host.
Keep track of your proteins today!

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